Fibromyalgia Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment by Guaifenesin.org May 25, 2022 written by Guaifenesin.org May 25, 2022 5 mins read Fibromyalgia is characterized by chronic widespread pain, fatigue, sleep disturbances and functional symptoms. The etiopathogenesis, diagnostic criteria and classification criteria of fibromyalgia are still debated and, consequently, so are the strategies for treating this condition. Fibromyalgia is the third most frequent musculoskeletal condition, and its prevalence increases with age. However, although diagnosis has improved with the evolution of more accurate diagnostic criteria, a considerable proportion of physicians still fail to recognize the syndrome. Many factors contribute to the development of fibromyalgia in a unique manner: genetic predisposition, personal experiences, emotional–cognitive factors, the mind–body relationship and a biopsychological ability to cope with stress. The multiple components of the pathogenesis and maintenance of the condition necessitate a multi-modal treatment approach. Individually tailored treatment is an important consideration, with the increasing recognition that different fibromyalgia subgroups exist with different clinical characteristics. Consequently, although an evidence-based approach to fibromyalgia management is always desirable, the approach of physicians is inevitably empirical, and must have the aim of creating a strong alliance with the patient and formulating shared, realistic treatment goals. Key points • Fibromyalgia is a fairly common syndrome in the general population, reaching a prevalence of 2–3% worldwide. • The complex polysymptomatology of fibromyalgia comprises not only chronic widespread pain, fatigue and sleep alterations but also autonomic disturbances, cognitive dysfunction, hypersensitivity to external stimuli, somatic symptoms and psychiatric disorders. • Owing to the subjectivity of the symptoms and the lack of biomarkers, diagnosis is exquisitely clinical, and diagnostic criteria are constantly evolving; early diagnosis and prevention are still elusive goals. • Fibromyalgia severity and progression or improvement can be evaluated by means of a plethora of composite tests. • Fibromyalgia pathogenesis is not fully understood; hypotheses state that genetic predisposition, stressful life events, peripheral (inflammatory) and central (cognitive–emotional) mechanisms interplay to create pain dysperception owing to neuromorphological modifications (‘nociplastic pain’). • Treatment should be multimodal and built on four pillars (patient education; fitness; pharmacotherapy; and psychotherapy); the approach should be individualized, symptom-based and stepwise, establishing shared goals with the patient. EffectiveFibromyalgiaguaifenesinguaifenesin dosageguaifenesin doseguaifenesin interactionsguaifenesin mechanism of actionguaifenesin side effectsguaifenesin warningsOptionTreatment 0 comment 0 FacebookTwitterPinterestEmail Guaifenesin.org next post Everything you need to know about fibromyalgia You may also like The Truth About Fibromyalgia and Chronic Fatigue Syndrome August 25, 2022 Why Use a Fibromyalgia Diet Plan? August 18, 2022 Fibromyalgia Natural Treatments, What Really Works? June 22, 2022 Fibromyalgia Chronic Fatigue Syndrome – What is Fibromyalgia? June 22, 2022 Get Rid of Fibromyalgia Pain With a Detox Colon Cleanse June 21, 2022 Chronic Insomnia, Nightmares and Bad Dreams, What Fibromyalgia Sufferers Need to Know! June 21, 2022 Fibromyalgia – New Treatments June 21, 2022 Combating Fibromyalgia With Flax Seed Oil June 21, 2022 Fibromyalgia – What Is It And Can Heat Therapy Help? June 21, 2022 What is the Hyaluronic Acid Fibromyalgia Link? June 21, 2022 Leave a Comment Cancel Reply Save my name, email, and website in this browser for the next time I comment.